Vitamin B12 (cobalamin) Price Trend and Forecast

Weekly Update
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Historical Data Since 2015
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Forecast for 2026
  • Commodity Pricing

vitamin b12 (cobalamin) Price Trends by Country

cnChina

Global vitamin b12 (cobalamin) Spot Market Prices, Trend Analysis and Forecast

Price-Watch™ provides real-time price assessments and price forecasts for Vitamin B12 Vitamin B12 (Cobalamin) across top trading regions: 

Vitamin B12 (Cobalamin) Regional Coverage Vitamin B12 (Cobalamin) Grade and Country Coverage Vitamin B12 (Cobalamin) Pricing Data Coverage Explanation
Asia-Pacific Vitamin B12 (Cobalamin) Pricing Analysis Vitamin B12 (Cobalamin) Food Grade >99% FOB Prices at Shanghai Port, China Weekly Price Update on Vitamin B12 (Cobalamin) Food Grade >99% Real-Time Export Prices from Shanghai Port, China to Global Markets
Vitamin B12 (Cobalamin) Feed Grade >1% FOB Prices at Shanghai Port, China Weekly Price Update on Vitamin B12 (Cobalamin) Feed Grade >1% Real-Time Export Prices from Shanghai Port, China to Global Markets
Vitamin B12 (Cobalamin) Food Grade >99% Ex-Zhejiang Domestic Prices, China Weekly Price Update on Vitamin B12 (Cobalamin) Food Grade >99% Real-Time Domestic Prices in Zhejiang, China
Vitamin B12 (Cobalamin) Feed Grade >1% Ex-Zhejiang Domestic Prices, China Weekly Price Update on Vitamin B12 (Cobalamin) Feed Grade >1% Real-Time Domestic Prices in Zhejiang, China

Vitamin B12 (Cobalamin) Price Trend Q1 2026

There have been notable signs of solid uptrends witnessed in the markets for Vitamin B12 (Cobalamin) in Q1 2026 for both its Food Grade (>99%) and Feed Grade (>1%). Vitamin B12 (Cobalamin) Food Grade has witnessed moderate price uptrends that have been boosted by continued demands from the pharmaceutical and nutraceutical industry sectors as well as consistent purchasing activity. On the other hand, Vitamin B12 (Cobalamin) Feed Grade has seen more pronounced price increases due to strong demand from the livestock and feed industries as well as restocking activities of premix suppliers.

China: Vitamin B12 (Cobalamin) Export prices FOB Shanghai, China

According to Price-Watch™ , in Q1 2026, Vitamin B12 (Cobalamin) Food Grade (>99%) prices in China have increased by 1.17%, supported by steady demand from pharmaceutical and nutraceutical sectors and balanced supply conditions. Meanwhile, Vitamin B12 (Cobalamin) Feed Grade (>1%) prices in China have risen more sharply by 5.16%, driven by strong demand from feed manufacturers and improved procurement activity.

The Vitamin B12 (Cobalamin) price trend in China has been influenced by firm demand across both high-purity and feed segments, along with tightening availability and stable production rates, which have collectively supported price increases during the quarter. In March 2026, Vitamin B12 (Cobalamin) Food Grade (>99%) prices in China increased by 8.57% due to a surge in export orders, limited spot availability, and increased demand from pharmaceutical formulations, while Vitamin B12 (Cobalamin) Feed Grade (>1%) prices in China rose sharply by 20.83% driven by aggressive stocking from the livestock sector, supply tightness and short-term demand spikes leading to a strong price surge toward the end of the quarter.

Vitamin B12 (Cobalamin) Price Trend Analysis: Q4 2025

In Q4 2025, the Vitamin B12 (Cobalamin) market has exhibited a slightly bearish trend across both Food Grade (>99%) and Feed Grade (>1%) segments.

Prices for Cyanocobalamin Food Grade have declined by around 1%, influenced by cautious procurement from nutraceutical and pharmaceutical sectors, along with stable supply conditions and adequate inventories.

Similarly, Vitamin B12 Feed Grade prices have softened by around 1–2%, reflecting moderate demand from feed and premix manufacturers and competitive domestic pricing.

Overall, the market has remained relatively stable but weak, with steady production rates and balanced supply-demand dynamics limiting any significant price movement.

China: Vitamin B12 (Cobalamin) Export prices FOB Shanghai, China

According to Price-Watch™, In Q4 2025, Vitamin B12 (Cobalamin) Food Grade (>99%) prices in China have declined slightly, registering a 1.04% quarter-on-quarter decrease. The softening has been attributed to subdued demand from pharmaceutical and nutraceutical sectors, along with sufficient inventory levels and stable production output.

Meanwhile, Vitamin B12 (Cobalamin) Feed Grade (>1%) prices in China have also decreased, reflecting a 1.76% decline during the quarter. The Vitamin B12 (Cobalamin) price trend in China has been driven by moderate demand from feed producers, balanced supply, and competitive pricing among manufacturers.

In December 2025, the Vitamin B12 (Cobalamin) Food Grade (>99%) prices in China has shown slight decrease with 0.35% and the Vitamin B12 (Cobalamin) Feed Grade (>1%) prices in China has also decreased with 0.81% as export activity has remained steady but not strong enough to support price recovery, with current market conditions expected to persist into the next quarter.

In Q3 2025, the global Vitamin B12 (Cobalamin) market reflected a firm and upward-trending sentiment, with distinct movement across Food Grade (Cyanocobalamin >99%) and Feed Grade (>1%) segments. Vitamin B12 (Cobalamin) Food Grade (Cyanocobalamin >99%) price trends were supported by steady pharmaceutical and nutraceutical demand, tighter availability, and increased export inquiries from major consuming regions, keeping quarterly price fluctuations within a moderate 4-6% range.

In contrast, Vitamin B12 (Cobalamin Feed Grade (>1%) experienced a milder but consistent upward adjustment driven by stable demand from feed and premix manufacturers, manageable inventory levels, and relatively controlled production output in China, resulting in fluctuations around 2-3% during the quarter.

Stable raw material markets, selective restocking activity, and constrained supply flexibility helped maintain upward momentum for both grades despite varied demand intensity across application sectors. Looking ahead, shifts in global supplement consumption, restocking patterns, and export competitiveness among Chinese producers are expected to shape Vitamin B12 (Cobalamin) price trend dynamics into the next quarter.

China: Vitamin B12 (Cobalamin) Export prices FOB Shanghai, China.

According to Price-Watch, In Q3 2025, Vitamin B12 (Cobalamin) Food Grade (Cyanocobalamin, >99%, USP, Powder) and Vitamin B12 (Cobalamin) Feed Grade (>1%, Powder) prices in China experienced upward adjustments supported by firmer demand and relatively tighter supply conditions. Cyanocobalamin Food Grade price trend in China strengthened as active procurement from pharmaceutical, nutraceutical, and fortified food sectors, coupled with limited production flexibility and higher export inquiries, pushed the market into the USD 1,420,000-1,460,000 per metric ton range.

Similarly, Vitamin B12 Feed Grade price trend rose amid stable demand from the feed and premix industries, moderate inventory levels, and steady operating rates among manufacturers, keeping prices within the USD 12,300-12,700 per metric ton range.

Market sentiment for both grades remained moderately bullish, supported by supply constraints, consistent downstream consumption, and improved export momentum. In September 2025, Cyanocobalamin Food Grade and Vitamin B12 Feed Grade price trends increased by 4.98% and 2.18%, respectively, driven by firm procurement activity and controlled supply, with these dynamics expected to influence pricing trends heading into the next quarter.

Vitamin B12 (Cobalamin) Price Trend Analysis: Q4 2024

Technical Specifications of Vitamin B12 (cobalamin) Price Trends

Product Description

Vitamin B12 (Cobalamin) is a water-soluble B-complex vitamin essential for red blood cell formation, neurological function, and DNA synthesis. It is industrially produced via microbial fermentation, most commonly using Pseudomonas denitrificans or Propionibacterium shermanii, and is available in several forms such as cyanocobalamin, methyl cobalamin, and hydroxocobalamin. Commercially, it is supplied in both food grade (>99%) and feed grade (>1%) concentrations, with the food grade primarily used in pharmaceuticals, dietary supplements, and fortified foods, while the feed grade is widely applied in animal nutrition to promote growth and prevent deficiency disorders.

Identifiers and Classification:

  • HS Code – 29362610
  • CAS No – 68-19-9
  • Molecular Formula – C63H88CoN14O14P
  • Molecular Weight[g/mol] – 1355.38 g/mol


Vitamin B12 (Cobalamin) Synonyms:

  • Cobalamin
  • Cynocobalamin


Vitamin B12 (Cobalamin) Grades Specific Price Assessment:

  • Vitamin B12 (Cobalamin) Food Grade (>99%) (Powder) Price Trend


Vitamin B12 (Cobalamin) Global Trade and Shipment Terms

  • Quotation Terms (Product & Country Specific): 10-11 MT
  • Packaging Type (Product & Country Specific): Bag


Incoterms Referenced in Vitamin B12 (Cobalamin) Price Reporting

Shipping Term  Location  Definition 
FOB Shanghai  Shanghai, China  Vitamin B12 (Cobalamin) Export price from China 
Ex-Zhejiang  Zhejiang, China  Domestically Traded Vitamin B12 (Cobalamin) price in China 

*Quotation Terms refers to the quantity range specified for the Vitamin B12 (Cobalamin) being quoted or offered in a commercial transaction.

**Packaging Type refers to standard packaging size commonly used for Vitamin B12 (Cobalamin) packing, ease of handling, transportation, and storage in industrial and commercial applications.

Key Vitamin B12 (Cobalamin) Producing Regions and Countries

Region  Country 
Shanghai  China 
Zhejiang  China 

Vitamin B12 (cobalamin) Industrial Applications

vitamin b12 market share end use

Historically, several events have caused significant fluctuations in Vitamin B12 (cobalamin) prices

Why Price Watch™?

Price Watch™ is your trusted resource for tracking global vitamin b12 (cobalamin) price trends. Our platform delivers real-time data and expert analysis, offering deep insights into the key factors driving price fluctuations in the vitamin b12 (cobalamin) market. By monitoring critical events such as geopolitical tensions, supply chain disruptions, and economic shifts, Price Watch™ keeps you fully informed of market dynamics.

In addition, Price Watch™ provides detailed forecasts and updates on production capacities, enabling you to anticipate market changes and make well-informed decisions. With Price Watch™, you gain a competitive edge in understanding all the elements that influence vitamin b12 (cobalamin) prices worldwide. Stay ahead of the curve with Price Watch’s™ reliable, accurate, and timely vitamin b12 (cobalamin) market data.

Track Price Watch's™ vitamin b12 (cobalamin) price assessment on a weekly basis since 2015 onwards, along with short-term forecasts, and get access to the detailed report in a downloadable format.

Vitamin B12 (cobalamin) Market Price Trend published by Price Watch™ reflect prevailing spot market conditions, derived from independent research, verified trade inputs, and proprietary market intelligence as of the publication date. Prices are published on the specified Incoterm and represent indicative base market levels, exclusive of applicable taxes, VAT, duties, tariffs, and other statutory charges. Actual transaction values may vary depending on volume, credit terms, contractual structure, and other negotiated conditions. Market prices are inherently subject to volatility, liquidity dynamics, regulatory changes, and evolving trade activity. The information provided is for reference and benchmarking purposes only and does not constitute an offer, recommendation, or guarantee of transactional outcomes. Users should exercise independent commercial judgment and assess their specific contractual, regulatory, tax, and application requirements before making business decisions. Price Watch™ assumes no liability for decisions taken based on this information.

Vitamin B12 (Cobalamin) is a water-soluble vitamin essential for red blood cell formation, neurological function, and DNA synthesis. It plays a critical role in preventing anemia and supporting nerve health. Vitamin B12 is widely used in pharmaceuticals, dietary supplements, food fortification, and animal feed applications. Common forms include Cyanocobalamin and Methylcobalamin, each used based on formulation and bioavailability requirements. Its price is important because it directly impacts the cost of vitamin supplements, fortified foods, pharmaceutical formulations, and feed premixes.

Due to its complex fermentation-based production process, Vitamin B12 pricing can be more volatile compared to other B vitamins, making it a key component in global nutrition and healthcare markets. Price-Watch™ tracks these prices to help businesses and consumers understand and stay updated with the market trends.

Vitamin B12 (Cobalamin) prices vary significantly depending on form (such as Cyanocobalamin or Methylcobalamin), purity, and region. Prices are typically quoted per kilogram due to its high potency and relatively low dosage requirements. Pricing fluctuates based on fermentation costs, raw material availability, production rates, and demand from pharmaceutical and nutraceutical industries. High-purity and specialty forms command premium prices. Price-Watch™ provides real-time price assessments across different global markets to help buyers and sellers make informed decisions.

Vitamin B12 (Cobalamin), prices are influenced by fermentation-based production costs, raw material inputs, and operating rates at manufacturing facilities. Demand from pharmaceuticals, dietary supplements, and animal feed sectors plays a key role in shaping market trends. Additional factors include energy costs, environmental regulations, export competition—particularly from China and inventory levels. Supply constraints or changes in fermentation yields can significantly impact pricing.

The largest consumers of Vitamin B12 include pharmaceutical and nutraceutical manufacturers, followed by the animal feed industry, particularly for poultry and livestock nutrition. Food and beverage companies also use B12 for fortification, especially in plant-based and fortified food products. Healthcare and specialty nutrition segments contribute additional demand. Price-Watch™ analyses demand patterns across all these industries.

Vitamin B12 is primarily produced through microbial fermentation using specific bacterial strains, followed by complex extraction and purification processes. This production method requires advanced biotechnology, controlled conditions, and specialized expertise. Manufacturing is concentrated in regions with strong fermentation capabilities and biotech infrastructure.

Global supply of Vitamin B12 generally meets demand; however, short-term imbalances can occur due to fermentation disruptions, plant maintenance, or regulatory inspections. Sudden increases in demand from pharmaceutical or nutraceutical sectors can tighten supply. Logistics disruptions may also impact availability. Price-Watch™ tracks production levels, export flows and trade patterns to help businesses understand global supply chains and identify sourcing opportunities.

Overall supply generally meets global demand but short-term tightness can occur due to plant maintenance shutdowns, environmental inspections or sudden demand increases from pharmaceutical or feed sectors. Regional imbalances may arise from logistics disruptions or regulatory constraints. Price-Watch™ monitors these supply-demand imbalances to alert the market about potential shortages or surpluses.

Vitamin B12 is available in pharmaceutical, food, and feed grades, as well as in different forms such as Cyanocobalamin and Methylcobalamin. Pharmaceutical-grade and specialty forms like Methylcobalamin command higher prices due to higher purity, bioavailability, and strict regulatory requirements. Feed-grade material is comparatively lower priced. Price-Watch™ provides separate price assessments for each grade to ensure market transparency.

A sudden increase in demand, particularly from supplement or pharmaceutical industries, can lead to price increases due to limited short-term supply flexibility in fermentation production. Suppliers may prioritize long-term contracts, reducing spot market availability and pushing prices upward. This can create short-term market volatility. Price-Watch™ captures these market dynamics in real-time.

Energy costs significantly impact Vitamin B12 production, especially due to the energy-intensive nature of fermentation and downstream purification processes. Rising electricity, steam, and fuel costs increase manufacturing expenses, which are often passed on to buyers. Transportation and logistics costs further influence final pricing. Price-Watch™ analyses in its price assessments & market reports.

Regional price variations arise from differences in production capacity, energy costs, labor expenses, regulatory compliance, and logistics. Import-dependent regions typically face higher prices due to freight and duties, while regions with strong fermentation infrastructure offer more competitive pricing. Price-Watch™ tracks prices across all major regions to highlight these differences.

The price outlook for Vitamin B12 depends on fermentation output, raw material and energy cost trends, demand from pharmaceutical and nutraceutical sectors, and global trade conditions. Inventory levels and macroeconomic factors also influence price direction. Price-Watch™ regularly publishes detailed forecasts that project price movements for the next 12 months based on comprehensive analysis of supply additions, demand growth in key industries, seasonal patterns, and macroeconomic indicators. Our forecasts help businesses anticipate market conditions and plan accordingly.

Absolutely. Accurate price forecasts enable buyers to plan procurement, manage inventories, negotiate long-term contracts, and control costs more effectively. If Price-Watch™ forecasts predict a price increase in three months, you might choose to stock up now or lock in long-term contracts at current rates, potentially saving thousands of dollars.

Global events such as pandemics, environmental inspections, plant shutdowns, energy shortages, trade restrictions, geopolitical tensions or logistics disruptions can significantly impact Vitamin B12 supply and pricing. Sudden changes in healthcare demand and nutrition demand can also create volatility. Price-Watch™ provides timely alerts when such events affect the market.

Price-Watch™ collects data from manufacturers, distributors, and buyers worldwide to publish regular price assessments, market reports, and forecasts. Our transparent methodology and comprehensive coverage make us a trusted source for understanding fair pricing and market trends in the Vitamin B12 (Cobalamin) industry.