ChinaIn Q1 2025, Vitamin B4 Choline Chloride 60% FOB Shanghai prices continued on an upward trajectory, reaching USD 620.33/MT, reflecting a +2.59% quarter-on-quarter gain. The animal feed sector maintained a steady pull for Choline Chloride, especially with increasing focus on feed efficiency and nutritional balance across intensive livestock operations. Export shipments remained stable, and domestic consumption held firm despite post-holiday slowdowns. While the market displayed signs of stabilization, players remained watchful of any shifts in corn and soybean meal prices that could indirectly influence choline chloride demand in compound feed formulations.
In Q1 2024, the market for Vitamin B4 Choline Chloride 60% FOB Shanghai witnessed a downward shift, with average prices settling at USD 594/MT, reflecting a -4.19% drop from the previous quarter. The decline was mainly influenced by weaker procurement activity from the animal feed industry, especially within poultry and swine segments. As livestock producers contended with disease outbreaks and soft meat consumption in some Asian regions, demand for feed additives including choline chloride was subdued. Producers maintained steady output levels, but slower offtake led to inventory build-up and price pressure.
In Q2 2024, the bearish trend persisted as prices declined further to USD 571.67/MT, a -3.76% quarter-on-quarter change. The Vitamin B4 Choline Chloride 60% FOB Shanghai market was weighed down by lackluster recovery in the animal nutrition sector, with many feed mills operating at reduced capacity. Additionally, limited recovery in aquaculture feed demand, combined with ample stock availability, led to softer FOB Shanghai prices. Chinese exporters also faced pricing pressure from competitors in Southeast Asia, leading to increased discounting and restrained profit margins.
In Q3 2024, Vitamin B4 Choline Chloride 60% FOB Shanghai market marked a marginal continuation of the declining trend, with prices reaching USD 566/MT, down -0.99% from Q2. However, the slowdown in the rate of decline suggested that prices were approaching a bottom. Some seasonal restocking began in preparation for the year-end livestock fattening cycle, particularly from major feed producers in South Asia. Although consumption remained below average, expectations of tighter supply ahead motivated cautious purchasing. Production rates were adjusted slightly downward by a few suppliers to mitigate further pricing losses.
In Q4 2024, the Vitamin B4 Choline Chloride 60% FOB Shanghai market rebounded sharply, with prices averaging USD 604.67/MT, a significant +6.83% increase quarter-on-quarter. The uptick was driven by revived demand from animal nutrition companies, as feed producers across Asia-Pacific ramped up purchases ahead of winter consumption peaks. Increased raw material costs and a slight tightening of supply, as some manufacturers performed maintenance shutdowns, also lent support to prices. Export demand from the Middle East and Africa further strengthened FOB offers from Chinese suppliers, marking a quarter of recovery for feed-grade choline chloride.
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Molecular Formula
Vitamin B4 is a water-soluble compound that plays a critical role in cellular energy production and genetic function. Unlike fat-soluble vitamins, adenine cannot be stored in significant amounts in the body and must be regularly obtained through the diet or supplements. Adenine is a fundamental component of nucleic acids (DNA and RNA), where it is essential for the storage and transmission of genetic information. It also forms part of adenosine triphosphate (ATP), the primary energy carrier in cells, supporting numerous metabolic processes and cellular growth. Due to its importance in energy metabolism and cellular repair, Vitamin B4 is widely used in nutritional supplements and pharmaceutical formulations aimed at enhancing vitality, supporting immune function, and promoting overall health. Regular intake of adenine is necessary to maintain optimal cellular function, especially during periods of rapid growth, recovery, or increased physical activity.
Packaging Type
Grades Covered
Incoterms Used
Synonym
PriceWatch Quotation Terms:
Ex-Location: This incoterm refers to a shipping agreement where the seller makes the goods available at their premises, and the buyer is responsible for all transportation costs, including shipping, insurance, and any other fees.
CIF: CIF refers to the Cost, Insurance, and Freight (CIF) terms for goods. Under CIF terms, the seller is responsible for the cost of goods, insurance, and freight charges until the goods reach the port of destination.
FD: FD stands for Free Delivered where the seller takes full responsibility for delivering goods to the location/port. This ensures the buyer receives the goods at the designated port with all necessary costs, except import duties, covered.
FOB: FOB refers to the Free On-Board shipping term, where the seller is responsible for the cost and risk of delivering the goods to the port. Once the goods are on board the vessel, the responsibility shifts to the buyer for all costs, including shipping and insurance.
| SL. NO. | ITEMS | SPECIFICATIONS | RESULT | |
| 1. | Assay (On a dry basis) | 98%-100.5% | 99.42% UV | |
| 2. | Ash Content | ≤0.05％ <0.01％ | GB 1903.36 | |
| 3. | Loss on Drying | ≤0.5％ 0.24％ | GB 5009.3 | |
| 4. | 1,4-Dioxane | ≤10ppm | Negative | |
| 5. | Pb | ≤2ppm | ≤2ppm | |
| 6. | As | ≤1ppm | <1ppm | |
| 7. | Hg | ≤1ppm | <1ppm | |
| 8. | Cd | ≤1ppm | <1ppm |
Applications
Vitamin B4 Choline Chloride is utilized across a range of industries including health, nutrition, pharmaceuticals, and biotechnology. Vitamin B4 Choline Chloride 60% is increasingly used in animal feed formulations to promote growth, enhance health, and improve overall productivity in livestock and poultry. Its role in cellular metabolism and energy production supports efficient nutrient utilization, muscle function, and immune response in animals. By supplementing feed with Vitamin B4, producers aim to boost feed conversion rates, support healthy development, and reduce the incidence of metabolic disorders, thereby improving animal performance and farm profitability. In addition to growth promotion, Vitamin B4 contributes to maintaining the health and resilience of animals under stress conditions such as disease, environmental changes, or intensive farming practices. It supports DNA and RNA synthesis, which is critical for tissue repair and regeneration, enhancing recovery from illness or injury. This makes it a valuable additive in feed for young, growing animals as well as breeding stock to ensure optimal reproductive health and longevity
Impact of U.S.–China Trade Tensions (2024–2025): By early 2025, Vitamin B4 prices in the United States surged significantly due to escalating trade tensions and the imposition of new tariffs on Chinese imports. The U.S., heavily reliant on China for both raw materials and finished Vitamin B4, faced higher input costs as a result of a 10% tariff, while China’s near monopoly in global nutraceuticals production gave it substantial leverage over pricing. These tariffs, compounded by retaliatory measures from China and ongoing supply chain difficulties, led to increased costs for U.S. manufacturers, who passed these on to consumers. The anticipation of further trade restrictions and supply interruptions prompted American buyers to increase procurement in advance, amplifying price volatility and reinforcing a bullish market sentiment.
High Production Costs and Limited Supply (2023): In 2023, the Vitamin B4 market experienced upward price pressure due to the high costs associated with its technically complex production processes and the limited global supply of raw materials. The synthesis of Vitamin B4, or adenine, requires premium inputs and specialized equipment, resulting in significant operational expenses for manufacturers. Additionally, strict regulatory compliance and fluctuating raw material prices further strained the industry, making it difficult to scale production and maintain competitive pricing. These challenges, combined with growing demand from the pharmaceutical and nutraceutical sectors, contributed to a noticeable increase in Vitamin B4 prices worldwide.
COVID-19 Pandemic and Demand Fluctuations (2020–2021): The onset of the COVID-19 pandemic led to significant volatility in Vitamin B4 prices, particularly as global supply chains were disrupted and demand patterns shifted. Early in the pandemic, supply shortages and transportation restrictions caused price spikes, especially in China, the world’s leading producer. As health awareness increased and the use of dietary supplements and fortified foods rose, demand for Vitamin B4 rebounded, supporting price recovery. However, ongoing uncertainties in logistics and procurement continued to contribute to price fluctuations throughout the pandemic period.
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Molecular Weight[g/mol]
CAS No
HS Code
Molecular Formula
Vitamin B4 is a water-soluble compound that plays a critical role in cellular energy production and genetic function. Unlike fat-soluble vitamins, adenine cannot be stored in significant amounts in the body and must be regularly obtained through the diet or supplements. Adenine is a fundamental component of nucleic acids (DNA and RNA), where it is essential for the storage and transmission of genetic information. It also forms part of adenosine triphosphate (ATP), the primary energy carrier in cells, supporting numerous metabolic processes and cellular growth. Due to its importance in energy metabolism and cellular repair, Vitamin B4 is widely used in nutritional supplements and pharmaceutical formulations aimed at enhancing vitality, supporting immune function, and promoting overall health. Regular intake of adenine is necessary to maintain optimal cellular function, especially during periods of rapid growth, recovery, or increased physical activity.
Packaging Type
Grades Covered
Incoterms Used
Synonym
PriceWatch Quotation Terms:
Ex-Location: This incoterm refers to a shipping agreement where the seller makes the goods available at their premises, and the buyer is responsible for all transportation costs, including shipping, insurance, and any other fees.
CIF: CIF refers to the Cost, Insurance, and Freight (CIF) terms for goods. Under CIF terms, the seller is responsible for the cost of goods, insurance, and freight charges until the goods reach the port of destination.
FD: FD stands for Free Delivered where the seller takes full responsibility for delivering goods to the location/port. This ensures the buyer receives the goods at the designated port with all necessary costs, except import duties, covered.
FOB: FOB refers to the Free On-Board shipping term, where the seller is responsible for the cost and risk of delivering the goods to the port. Once the goods are on board the vessel, the responsibility shifts to the buyer for all costs, including shipping and insurance.
| SL. NO. | ITEMS | SPECIFICATIONS | RESULT | |
| 1. | Assay (On a dry basis) | 98%-100.5% | 99.42% UV | |
| 2. | Ash Content | ≤0.05％ <0.01％ | GB 1903.36 | |
| 3. | Loss on Drying | ≤0.5％ 0.24％ | GB 5009.3 | |
| 4. | 1,4-Dioxane | ≤10ppm | Negative | |
| 5. | Pb | ≤2ppm | ≤2ppm | |
| 6. | As | ≤1ppm | <1ppm | |
| 7. | Hg | ≤1ppm | <1ppm | |
| 8. | Cd | ≤1ppm | <1ppm |
Applications
Vitamin B4 Choline Chloride is utilized across a range of industries including health, nutrition, pharmaceuticals, and biotechnology. Vitamin B4 Choline Chloride 60% is increasingly used in animal feed formulations to promote growth, enhance health, and improve overall productivity in livestock and poultry. Its role in cellular metabolism and energy production supports efficient nutrient utilization, muscle function, and immune response in animals. By supplementing feed with Vitamin B4, producers aim to boost feed conversion rates, support healthy development, and reduce the incidence of metabolic disorders, thereby improving animal performance and farm profitability. In addition to growth promotion, Vitamin B4 contributes to maintaining the health and resilience of animals under stress conditions such as disease, environmental changes, or intensive farming practices. It supports DNA and RNA synthesis, which is critical for tissue repair and regeneration, enhancing recovery from illness or injury. This makes it a valuable additive in feed for young, growing animals as well as breeding stock to ensure optimal reproductive health and longevity
The dynamics of supply and demand, manufacturing costs, and logistical considerations all affect the price of vitamin B4 (adenine) on the international market. Rising demand, particularly from the nutraceutical and animal feed industries, coupled with tight global supply and restricted stock in strategic places, has caused prices to rise. Notably, prices have increased when factory activity and export orders rise in major producing nations like China. Price volatility is further exacerbated by rising production and raw material costs, the depreciation of the Chinese yuan, and currency fluctuations, which increase costs for manufacturers and make exports more appealing.
Supply chain disruptions, such as production slowdowns, shipping delays, and port congestion, reduce the availability of Vitamin B4 and drive up prices. When key suppliers like China face logistical challenges or export restrictions, importers compete for limited stock, leading to higher costs and increased market volatility. These factors make it essential for buyers to plan procurement carefully and maintain flexible supply strategies. Proactive communication with suppliers and diversified sourcing can help mitigate risks associated with these disruptions.
Regional price differences for Vitamin B4 are notable, with the U.S. facing higher prices due to strong demand, supply constraints and logistical issues like port congestion and wildfires. China offers lower prices but export slowdowns and stockpiling can tighten supply temporarily. Procurement heads should monitor supply risks, secure contracts early, diversify suppliers, and maintain flexible inventories to manage price volatility. Additionally, working closely with logistics partners and exploring alternative sourcing can help ensure steady supply and cost control.
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